Fish oil supplements are associated with an increased risk of atrial fibrillation (AFib) in certain high-risk patients, according to a new meta-analysis published in the European Heart Journal: Cardiovascular Pharmacotherapy.
The authors note that the research in this area has led to a variety of conclusions, and show how they evaluated data from five different randomized controlled trials. In total, their analysis included data from more than 50,000 patients taking either fish oil supplements or a placebo. All patients were followed for at least two years and some for more than seven years.
Overall, the authors found that taking fish oil supplements was associated with a “significantly higher” risk of developing AFib than taking placebo in patients with elevated plasma triglycerides. The incidence rate was 1.37.